Nucleosides, Nucleotides and their Biological Applications by Janet L Rideout

By Janet L Rideout

Nucleosides, Nucleotides, and Their organic functions includes the complaints of the 5th foreign around desk on Nucleosides, Nucleotides, and Their organic purposes held at learn Triangle Park, North Carolina on October 20-22, 1982. participants specialise in the organic purposes of nucleosides and nucleotides, in addition to advances in artificial chemistry. subject variety from fast-moving biochemical matters resembling the 2',5'-oligoadenylates and their courting to interferons; adenosine and adenine nucleotide receptors; and nucleosides with selective antiviral motion.
This quantity is equipped into eleven chapters and starts with an outline of nucleosides which are used as antiviral brokers and their mechanism of motion, together with idoxuridine, vidarabine, and trifluridine. The dialogue then shifts to the chemical and organic houses of nucleosides of purines and ring analogs; 2'-fluoroarabinosyl pyrimidines and purine-like C-nucleosides; and the potential for 2',5'-oligoadenylates as chemotherapeutic brokers. The reader is additionally brought to receptors for adenosine and adenine nucleotides; the functionality of pyrrolo[2,3-d]pyrimidine nucleosides in polynucleotides; and weird nucleoside synthons and oligonucleotide synthesis. A bankruptcy at the synthesis of flexible C-nucleoside precursors and likely C-nucleosides concludes the e-book.
This publication may be of worth to chemists, biologists, and people with an curiosity in nucleosides and nucleotides.

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